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Cats with Feline Infectious Peritonitis:
A Treatment Guide

Table of Сontents

1. Feline Infectious Peritonitis Overview

  • What is FIP in cats

  • Learn about cat coronavirus

2. FIP Classification and Symptoms

  • FIP in cats symptoms

  • Classification of FIP

  • FIP diagnosis and prognosis

3. FIP Treatment For Cats

  • FIP cat treatment overview

  • How does GS-441524 work?

  • GS-441524 effectiveness

  • GS-441524 side effects

  • Important results

4. FIP GS Treatment Schedule and Use

  • FIP treatment guidelines and duration

  • How is FIP cat treatment administered?

  • How do I properly perform gs-441524 injections?

  • When to stop 

5. FIP GS441524 Dosage

  • How to find right treatment dosage

  • About FIP calculator

  • How to adjust dosage

  • Find next steps you need to take

About This Guide

This guide covers everything you need to know about FIP, from the causes of FIP in cats to the different symptoms and forms of the disease.

Learn about FIP treatment, including how to determine the right dosage and how to inject it, as well as the treatment's guidelines, efficacy, and potential side effects.

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​We understand you are in a hurry, but please take a moment to read through this FIP guide, which contains important information about FIP and GS treatment recommendations. Let's get started!

FELINE INFECTIOUS PERITONITIS OVERVIEW

WHAT IS FIP IN CATS?

Feline Infectious Peritonitis (FIP) is an uncommon, progressive and deadly disease that can cause severe inflammation and damage to the internal organs, and is usually fatal.

What Causes Fip in Cats?

FIP is caused by mutated intestinal coronavirus that infects the cat’s white blood cells, which carry the infection throughout the body, triggering an intense immune system response. 

  • FIP can occur in any cat that is exposed to the feline coronavirus (FCoV). ​

  • The coronavirus that causes FIP infects only cats.

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What it Does?

FIP causes affected tissues to become red and swollen, including the intestines, brain, and other organs.

Once FIP has infected one or more organs or body systems, it spreads quickly and almost always kills a cat that is infected.

  • FIP spreads throughout the body using cat's own immune system.

  • Causes severe inflammatory reaction in tissues.

  • Commonly affects intestines, lungs, liver, abdomen, kidney or brain.

FIP SYMPTOMS AND CLASSIFICATION

FIP SYMPTOMS

Many people report that their cat's symptoms appeared suddenly. This is likely because cats can hide illness until they are very sick. The first signs are often not very clear:

  • Unexplained weight loss

  • Depression

  • Anorexia

  • Unresponsive chronic fever

Signs of FIP arise weeks, months, and in rare cases years after initial infection.

FIP FORMS

More specific signs of FIP vary depending on the form of the disease and the organs that are involved. FIP is generally classified into two types:

Effusive FIP (wet) - causes abdominal or chest fluid accumulation and is considered more lethal.
 

Non-effusive FIP (dry) - progresses slowly and does not cause much fluid buildup.

  • Both forms are fatal.

  • It's possible for one cat to experience symptoms of both the wet and dry forms at the same time. 

  • Either form can also lead to both ocular and neurologic symptoms.

MAIN FIP CAT SYMPTOMS: 

  • Loss of appetite

  • Dull fur

  • Diarrhea

  • Vomiting

  • Stunted growth

WET FIP SYMPTOMS:

  • Fluid build-up in the abdomen (Potbelly)

  • Fluid build-up in the chest (respiratory issues)

DRY FIP SYMPTOMS:

  • Anemia

  • Antibiotic-resistant fever

NEUROLOGICAL FIP SYMPTOMS:

  • Seizures

  • Dementia

  • Lack of coordination

  • Inability to jump

  • Ataxia (Muscle weakness, especially noticeable in the back legs)

OCULAR FIP SYMPTOMS:

  • Eye inflammation

  • Eye discoloration or cloudiness

  • Blindness

FIP TREATMENT FOR CATS

GS-441524 TREATMENT INTRO

In the recent years FIP disease has progressed from being fatal, with most veterinarians recommending euthanasia, to being treatable.

Since mid-2019, when GS-441524, an experimental anti-viral drug (nucleoside analog), successfully cured FIP in clinical trials, tens of thousands of cat owners worldwide have been able to cure their cats of FIP.

How fast does gs-441524 work?

If the medication is administered correctly and on time, your cat should begin to feel better within a few days, with no serious side effects.

How it works?

GS-441524, which inhibits the earliest stage of viral RNA replication. In other words GS defeats viruses by blocking their ability to replicate.

Is There a Minimum Age Requirement?

GS is appropriate for cats of all ages with infectious peritonitis symptoms, particularly young cats. 

How Dangerous Is It?

GS demonstrated to be non-toxic and effective at inhibiting replication of FIP-associated FCoV strains.

The wrong treatment can harm a cat with suspected FIP, so only consider it after a definitive diagnosis.

GS TREATMENT SCHEDULE AND USE

GS FIP TREATMENT INFORMATION AND DURATION

The recommended length of treatment is 12 weeks and requires daily injections.

However, the actual treatment length may depend on many factors such as how quickly your cat responds to the treatment, the stage of the FIP infection when you began the treatment, and your personal financial situation.

The duration of treatment depends on how quickly your cat recovers and how severe the FIP infection was at the beginning of treatment.

As the wrong treatment can harm a cat, treatment of cats with suspected FIP should only be considered after all efforts have been made to obtain a definitive diagnosis.

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FIP Treatment Recomendations:

  • FIP disease is not like a common viral inflammatory disease, and it needs to be treated carefully and watched closely!​
     

  • GS-441524 should be given to cats every day for 84 days (12 weeks).
     

  • It is very important that you understand how your pet’s injectable medication needs to be given.

  • The GS441524 injection is given in the fatty tissue, just under the skin delivering immediate treatment straight to your cat's bloodstream. 

  • Always use a new needle for each dose and record the time and date of every shot!

  • Before beginning, consult your veterinarian for training and guidance on how to administer injectable medication to your cat. If you are uncomfortable, request additional training.​

FINDING THE RIGHT GS DOSAGE

FINDING THE RIGHT DOSE

  • Your cat's dosage depends on his or her weight the severity of the symptoms.
     

  • Higher doses are required for more severe symptoms.
     

  • The dose should be adjusted based on the cat's weight throughout the entire 84-day treatment.

FIP Dosage Calculator:

Every cat is different, and therefore will require a different dosage of GS to effectively treat their FIP. The GS FIP treatment calculator takes into account all the important factors, such as your cat's weight, symptoms, and expected weight changes to determine the perfect dosage for your feline friend. 

With this information in hand, you can be confident that you are giving your cat the GS they need to fight off their FIP and live a long and healthy life.

DOSAGE CHART FOR GS

Wet Form FIP (Abdominal Effusion):

  • Symptoms: Increased fluid in the abdomen area (causes a pot-bellied appearance).

  • Dosage: (5 mg/kg)

Wet Form FIP (Thoracic Effusion):

  • Symptoms: Fluids in chest (hard for the cat to breathe).

  • Dosage: (6 mg/kg)​

Dry Form FIP (non-effusive):

  • Symptoms: Excessive thirst and urination, vomiting, weight loss, jaundice and/or organ inflammation.

  • Dosage: (6 mg/kg)

Ocular FIP:

  • Symptoms: Swelling in the eyes or any damage or abnormal change in the eye tissue.

  • Dosage: (8 mg/kg)

Neurological FIP:

  • Symptoms: Nervous tissue damage: Seizures or blindness, movement in an abnormal or uncoordinated way.

  • Dosage: (10 mg/kg)

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VISIT OUR CALCULATOR PAGE TO: 

  • Determine the Cost of a Full 84-Day Treatment.

 

  • Obtain the Recommended Daily Dose.
     

  • Estimate the number of vials required.
     

  • Determine the volume of Gs in milliliters required for a full 84-day treatment.